Compensating functional iron deficiency in patients with allergies with targeted micronutrition

Summary Iron deficiency is associated with atopy. during pregnancy increases the risk of atopic diseases in children, while both allergic children and adults are more likely to have iron anemia. Immunologically, leads activation antigen-presenting cells, promotion Th2 cells enables antibody class switch B cells. In addition, primes mast for degranulation, an increase their content inhibits degranulation. Many allergens, especially those lipocalin lipocalin-like protein structures, able bind either deprive or supply this trace element immune Thus, a local induced will result sensitization. However, proteins such as whey β‑lactoglobulin (BLG) can also transport micronutrients into defense (holo-BLG: BLG micronutrients) hinder activation, thereby promoting tolerance protecting against allergy. Since 2019, several clinical trials been conducted subjects using holo-BLG supplementary balanced diet, leading reduction symptom burden. Supplementation specifically supplied therefore represents new dietary approach compensate functional allergy sufferers.